https://ojs.luminescience.cn/JCD <p>Journal of Cancer Discovery (JCD) is an open access, peer-reviewed journal publishing original articles, convincing and practical reviews, authoritative clinical studies, short communications as well as perspectives that report cutting-edge advances and the latest research findings in the rapidly changing field of cancer discovery. The journal gives strong emphasis to basic, translational and clinical research and aims to serve as a platform for global scientists, clinicians, policy makers as well as the general public to discuss and share the up-to-date information regarding the early prevention, detection, diagnosis, cure and rehabilitation of cancer. Manuscripts are stringently reviewed for high standards of scientific merit, and only those that report results of novelty and scientific soundness will be considered for publication in this journal.</p> <p> </p> <p>Topics include but are not limited to the following:</p> <p> </p> <p><strong>• Cancer genetics and genomics</strong>: new chromosomal, molecular or epigenetic alterations in benign and malignant diseases; chromosomal rearrangements or genomic alterations in cancer cells; molecular genetics of cancer predisposition; DNA damage and repair.</p> <p> </p> <p><strong>• Cancer systems biology</strong>: experimental biology, computational modeling, multi-dimensional data analysis as well as systems engineering which are applied to cancer diagnosis and treatment. </p> <p> </p> <p><strong>• Growth promoting signals and growth inhibitory signals</strong>: dysregulation of growth factor signaling pathways and cell cycle progression; proto-oncogenes and their activation; dysregulation of quiescence and differentiation; tumor suppressors and their inactivation.</p> <p> </p> <p><strong>• Cancer stem cells (CSCs)</strong>: accurate targeting of CSCs; CSC markers, such as CD133, CD44, EpCAM, ALDH, CD90, etc.; resistance mechanisms of CSCs; drug efflux activity of CSCs; vasculogenic mimicry (VM) in CSCs.</p> <p> </p> <p><strong>• Tumor metabolism, metastasis and immunology</strong>: pathways and metabolism in tumor cells; pathogenesis based on immune microenvironment and metabolism; precision diagnosis and treatment of major cancers based on multi-omics.</p> <p> </p> <p><strong>• Carcinogenesis</strong>: mechanisms involved in chemical-, environmental-, physical (radiation, trauma, etc.)-, infection, inflammation-associated cancer development and molecular cancer epidemiology.</p> <p> </p> <p><strong>• Cancer prevention</strong>: preclinical studies on preventive interventions and their mechanisms, including chemoprevention, immunoprevention (checkpoint inhibitors, immunological approaches to prevention, and vaccination) and nutritional/behavioral prevention; clinical studies on preventive interventions; dissemination and implementation research; health policy and global cancer control studies. </p> <p> </p> <p><strong>• Cancer therapy studies</strong>: clinical research that impacts on the treatment of cancer using systemic chemotherapy, immunotherapy, targeted therapy, radiation, gene therapy, vaccine- and antibody-based cancer therapy and combination therapy; therapy resistance mechanisms, such as cell survival signaling, cell death inhibition, drug inactivation and efflux.</p> <p> </p> <p><strong>• Cancer-associated studies</strong>: cancer pain &amp; malnutrition, cachexia, symptoms relevant to treatment, and psychosocial studies on cancer.</p> <p> </p> <p>If you have any queries about our journal or have any questions want to discuss with our Editors-in-Chief, please contact us at: <a href="mailto:editor-jcd@luminescience-press.com">editor-jcd@luminescience-press.com</a>, and we sincerely expect to hear from you.</p> en-US https://ojs.luminescience.cn/JCD/announcement/view/9 <p><a href="https://file.luminescience.cn/Call%20for papers-JCD20210910115027.pdf">Call for Papers-Journal of Cancer Discovery</a></p> Journal of Cancer Discovery 2021-09-10 https://ojs.luminescience.cn/JCD/announcement/view/6 <p><strong>What to Know Before You Hit </strong><strong>“</strong><strong>Submit</strong><strong>”</strong></p> <p> </p> <p>1. Why publish with Luminescience?</p> <p>All our journals are open accessed, peer-reviewed and bilingually published both in English and Chinese, that means your research results publishing in our journals can be accessed by worldwide scholars without subscription block or language barrier and will get its full impact as it deserves.</p> <p> </p> <p>Publishing your article with Luminescience will benefit you from:</p> <ul> <li>Online and high-efficient publication</li> <li>Open Access and global dissemination</li> <li>Access in China without language barrier</li> </ul> <p> </p> <p>2. How does it cost for publishing in our journals?</p> <p>While unlike most open access journals, which are free to readers but charge from authors for APC or publication fee, Luminescience has instituted a generous waiver policy for our journals till July31,2022, that means peer review, basic copyediting, typesetting for publication will be free for authors. Only manuscripts that need extensive English editing, translation, or figure/image optimization, cost will be charged for these extra services.</p> <p> </p> <p>3. How do I find guidelines or instructions for authors for my specific journal?</p> <p>Each Luminescience journal has its own manuscript Submission Guidelines. Go to the list of <a href="https://luminescience.cn/journals"><u>Luminescience Journals</u></a>, select your target journal and view the journal page, in the top navigation bar, you can find Submission Guidelines.</p> <p> </p> <p>4. When will I know if my article has been accepted?</p> <p>Luminescience strictly follows a systematic editorial process embedding a quality control mechanism outlined by the <a href="https://publicationethics.org/">COPE</a>, the <a href="https://doaj.org/">DOAJ</a>, the <a href="https://oaspa.org/">OASPA</a>, and the <a href="http://www.wame.org/">WAME</a>. Manuscripts submitted to our journals will be scrutinized critically by the editorial and peer review. The working flow for each manuscript can be trackable via our submission system and our editors will inform the authors for any status updates for the next procedure.</p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p> Journal of Cancer Discovery 2021-07-14