https://ojs.luminescience.cn/CDS <p><em>Cardiospace</em> is an international, open access and peer-reviewed journal that reports the latest research findings and practical approaches to the diagnosis, therapy and prevention of cardiovascular disease. It aims to publish the high quality manuscripts covering original basic and clinical research on all aspects of cardiovascular medicine and build a scientific platform for researchers in the world. </p> Luminescience Press en-US Cardiospace 2957-692X <p>Copyright licenses detail the rights for publication, distribution, and use of research. Open Access articles published by Luminescience do not require transfer of copyright, as the copyright remains with the author. In opting for open access, the author(s) should agree to publish the article under the CC BY license (Creative Commons Attribution 4.0 International License). The CC BY license allows for maximum dissemination and re-use of open access materials and is preferred by many research funding bodies. Under this license, users are free to share (copy, distribute and transmit) and remix (adapt) the contribution, including for commercial purposes, providing they attribute the contribution in the manner specified by the author or licensor.</p> https://ojs.luminescience.cn/CDS/article/view/121 <p>This article aims to study the etiological and clinical profile of acute heart failure in Angola and to identify the predictors associated with in-hospital mortality. Methods: A descriptive, observational, cross-sectional study was carried out in a tertiary public hospital in Angola. Information on demographic and biological data was collected. The following variables were included: demographic, etiological, and clinical characteristics, cardiovascular risk factors, precipitating factors of cardiac decompensation, comorbidities, and complications. In the univariate analysis we evaluated absolute and relative frequency, in the bivariate analysis independent Mann-Whitney Test, T Student test, and Chi-Square, tests were used as appropriate. Results: The sample comprises 257 individuals, of which 114 (44.36%) are male. The mean age is 49.90 ± 15.95 years. Hospital mortality is 23%. Predictors of poor prognosis were male sex (56.67% vs 40.61%, <em>p</em> = 0.037), lower systolic, diastolic, and mean blood pressure ((mean = 115 mmHg vs 138 mmHg, <em>p</em><em> </em>&lt; 0.001; mean = 73 mmHg vs. 85 mmHg, <em>p</em><em> </em>&lt; 0.001 and mean = 87.55 mmHg vs 102.74 mmHg; <em>p</em><em> </em>&lt; 0.001, respectively), higher respiratory rate (mean = 26.48 vs 24.00, <em>p</em><em> </em>= 0.013), New York Health Association (NYHA) Class IV (60.00% vs 35.03%, <em>p</em><em> </em>&lt; 0.001) and lower LVEF (mean = 34.90% vs 39.7%, <em>p</em><em> </em>= 0.013) Infection as a precipitating cause of cardiac decompensation, a previous history of pulmonary TB and DCM were also associated with higher in-hospital mortality (61.66% vs 26.39%, <em>p</em><em> </em>&lt; 0.001; 33.33% vs 12.69 <em>p</em> &lt; 0.001, and 45.00% vs 29.95%, <em>p</em> = 0.031; respectively). Conclusions: The results indicate that in Angola, heart failure affects young and middle-aged patients and is associated with high in-hospital mortality.</p> Humberto Morais Artur Alfredo Isaura Lopes Mauer A.A. Gonçalves Copyright © 2023 Humberto Morais, Artur Alfredo, Isaura Lopes, Mauer A.A. Gonçalves https://creativecommons.org/licenses/by/4.0/ 2022-12-30 2022-12-30 1 11 10.55976/cds.2202311211-11