https://ojs.luminescience.cn/CDS/issue/feed Cardiospace 2022-12-30T00:00:00+08:00 Editorial Office of CDS editor-cds@luminescience-press.com Open Journal Systems <p><em>Cardiospace</em> is an international, open access and peer-reviewed journal that reports the latest research findings and practical approaches to the diagnosis, therapy and prevention of cardiovascular disease. It aims to publish the high quality manuscripts covering original basic and clinical research on all aspects of cardiovascular medicine and build a scientific platform for researchers in the world. </p> https://ojs.luminescience.cn/CDS/article/view/121 Etiology, clinical features, comorbidities and mortality in patients with acute heart failure. Experience of a tertiary public hospital in Angola 2022-09-23T11:01:08+08:00 Humberto Morais hmorais1@gmail.com Artur Alfredo alfredoarturdealmeida@gmail.com Isaura Lopes isalopes222@gmail.com Mauer A.A. Gonçalves mauergoncalves@gmail.com <p>This article aims to study the etiological and clinical profile of acute heart failure in Angola and to identify the predictors associated with in-hospital mortality. Methods: A descriptive, observational, cross-sectional study was carried out in a tertiary public hospital in Angola. Information on demographic and biological data was collected. The following variables were included: demographic, etiological, and clinical characteristics, cardiovascular risk factors, precipitating factors of cardiac decompensation, comorbidities, and complications. In the univariate analysis we evaluated absolute and relative frequency, in the bivariate analysis independent Mann-Whitney Test, T Student test, and Chi-Square, tests were used as appropriate. Results: The sample comprises 257 individuals, of which 114 (44.36%) are male. The mean age is 49.90 ± 15.95 years. Hospital mortality is 23%. Predictors of poor prognosis were male sex (56.67% vs 40.61%, <em>p</em> = 0.037), lower systolic, diastolic, and mean blood pressure ((mean = 115 mmHg vs 138 mmHg, <em>p</em><em> </em>&lt; 0.001; mean = 73 mmHg vs. 85 mmHg, <em>p</em><em> </em>&lt; 0.001 and mean = 87.55 mmHg vs 102.74 mmHg; <em>p</em><em> </em>&lt; 0.001, respectively), higher respiratory rate (mean = 26.48 vs 24.00, <em>p</em><em> </em>= 0.013), New York Health Association (NYHA) Class IV (60.00% vs 35.03%, <em>p</em><em> </em>&lt; 0.001) and lower LVEF (mean = 34.90% vs 39.7%, <em>p</em><em> </em>= 0.013) Infection as a precipitating cause of cardiac decompensation, a previous history of pulmonary TB and DCM were also associated with higher in-hospital mortality (61.66% vs 26.39%, <em>p</em><em> </em>&lt; 0.001; 33.33% vs 12.69 <em>p</em> &lt; 0.001, and 45.00% vs 29.95%, <em>p</em> = 0.031; respectively). Conclusions: The results indicate that in Angola, heart failure affects young and middle-aged patients and is associated with high in-hospital mortality.</p> 2022-12-30T00:00:00+08:00 Copyright © 2023 Humberto Morais, Artur Alfredo, Isaura Lopes, Mauer A.A. Gonçalves